Dimethylformamide is an organic compound with the formula ch 3 2 ncoh. Dimethylformamide is odorless whereas technical grade or degraded samples often have a fishy smell due to impurity of. The user must determine suitability of this information for his application. Search results for dimethylformamide at sigmaaldrich. Details of the supplier of the safety data sheet emergency telephone number for information us call. Dimethylformamide dmf is a widely used solvent used in the synthetic resin and leather industries that causes doserelated massive necrosis in animals 3 and is capable of producing focal hepatic necrosis and microvesicular steatosis in humans, the severity of which correlates with the duration of occupational exposure. This conclusion, however, was the result of an artefact. Dimethylamine degradation impurities can be removed by sparging degraded samples with an inert gas such as argon or by sonicating the samples under reduced pressure. Buy n,ndimethylformamide cas 68122, a strongly polar organic solvent, from santa cruz. Dimethylformamide is odorless, but technicalgrade or degraded samples often have a fishy smell due to impurity of dimethylamine. The international chemical safety card icsc 0457 for n,ndimethylformamide, produced by the international programme on chemical safety ipcs, 1999, has also been reproduced in this document.
Remove contact lenses, if present, after the first 5 minutes, then continue rinsing. N,n dimethylformamide is a derivative of formamide, whereby the amino hydrogens are replaced by methyl groups. N,ndimethylformamide for headspace gas chromatography suprasolv. Its health effects include hepatotoxicity and male reproductoxicity, possibly linked with mitochondrial dna mtdna alterations including mtdna common deletion deltamtdna4977 and. Our team decides the composition and grades as per the requirement and specification from the client. Dimethylformamide other means of identification product no 92, 5362, 9344, 4929, 9222, 9221, 9220 recommended use and restriction on use recommended use. List of all languages of msds for eastmantm 2ethylhexanol. The international chemical safety card icsc 0457 for n,n dimethylformamide, produced by the international programme on chemical safety ipcs, 1999, has also been reproduced in this document. Workers may be harmed from exposure to dimethylformamide. View or download the n,n dimethylformamide msds material safety data sheet or sds for from merck.
Msds examples sds sheets msds authoring services inc. N,ndimethylformamide cas 68122 100202 emd millipore. Symptoms of acute exposure in humans include abdominal pain, nausea. May also indicate that the same chemical with the same cas number appears on another list with a different chemical name. This sds, and the associated product, is intended for use only by technically qualified. Companies may have immediate legal obligations following the inclusion of a substance in the candidate list on this website including in particular articles 7, 31 and 33 of the reach regulation. N, ndimethylformamide dmf is a clear liquid that has been widely used in industries as a solvent, an additive, or an intermediate because of its extensive miscibility with water and most common organic solvents. N,ndimethyl formamide cas no 68122 material safety data sheet sdsmsds. Cdc niosh publications and products preventing adverse. None information in this msds is from available published sources and is believed to be accurate. Dimethylformamide an overview sciencedirect topics. Dimethylformamide dmf manufacturers, suppliers and exporters. It can harm the eyes, skin, lungs, liver, and heart. The level of exposure depends upon the dose, duration, and work being done.
Uses advised against food, drug, pesticide or biocidal product use. Dimethylformamide is odorless whereas technical grade or degraded samples often have a fishy smell due to impurity of dimethylamine. As its name indicates, it is a derivative of formamide, the amide of formic acid. Identification product name n,ndimethylformamided7 casno 4472417 synonyms no information available recommended use laboratory chemicals. N,ndimethylformamide is considered to be a potent liver toxin. Dimethylformamide has been measured in ambient air near a fibre plant and near waste facilities. Listed as a hazardous air pollutant hap generally known or suspected to cause serious health problems. No warranty, express or implied, is made and labchem inc. Chemical product and company identification product name. The test atmosphere had a relative humidity of 68% and was at.
Product name n,n dimethylformamide d7 casno 4472417 synonyms no information available recommended use laboratory chemicals. Under the new ghs, globally harmonized system, the name has been changed from msds, material safety data sheet, and simplified to sds, safety data sheet. N,n dimethylformamide is considered to be a potent liver toxin. As a msds service provider, we are specialists in ghs. This material does not contain any class 1 ozone depletors. Sds of n,ndiethylformamide, safety data sheets, cas 617845.
An msds material safety data sheet once was a ninesection chemical safety document detailing the toxicity, use, storage, handling and emergency procedures of hazardous substances. Sections i health hazard assessments for noncarcinogenic effects and. Draft background document for n,ndimethylformamide dmf document developed in the context of echas fifth recommendation for the inclusion of substances in annex xiv information comprising confidential comments submitted during public consultation, or relating to content of registration dossiers which is of. Transport the samples and corresponding paperwork to the lab. Msds authoring services specialize in msds writing, creation, development and authoring.
Although they are seldom mixed for use, mixed exposure sometimes takes place in a synthetic fiber plant in certain working situations. Draft background document for n,n dimethylformamide dmf. Hazard statements h226 flammable liquid and vapour. Submit bulk samples in a separate container to prevent contamination of charcoal tube samples. N,n dimethylformamide msds material safety data sheet or sds, coa and coq. Dimethylformamide, monomethylacetamide, monomethylformamide, occupational health, urinalysis both n,ndimethylformamide dmf and n,ndimethylacetamide dma are potentially hepatotoxic industrial solvents15.
N,n dimethylformamide is a member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups. It is a volatile organic compound and a member of formamides. N,n,dimethylformamide is produced, as an intermediate or a final product, by process units covered under this subpart. This organic solvent is used in acrylic fiber spinning, chemical manufacturing, and pharmaceutical production.
N,ndimethylformamide 68122 hazard summary dimethylformamide is used as an industrial solvent and in the production of fibers, films, and surface coatings. N,ndimethylformamide msds material safety data sheet or sds, coa and coq. Only the candidate list published on this website is deemed authentic. Application n,n dimethylformamide was used to solubilize mtt crystals in cell viability assays. Hconch32 material safety data sheet n,ndimethylformamide msds. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Dmf is a polar hydrophilic aprotic solvent with a high boiling point. Msds dimethylformamide page 1 of 9 material safety data sheet. Toxicity data skin rabbit 4,720 mgkg ld50 oral rat 2,800 mgkg ld50 6 hr. Acute shortterm exposure to dimethylformamide has been observed to damage the liver in animals and in humans. First aid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. N,ndimethylformamide cas 68122 822275 emd millipore.
Dimethylformamide solvent for peptide coupling, used as a wash after each deprotection and coupling step in tboc, used as a solvent in fmoc, solvent with low evaporation rate, catalyst in synthesis of acid halides. Our supply position is ensured by prompt delivery of our chemical pr. Identification of the substancemixture and of the companyundertaking 1. Commonly abbreviated as dmf although this initialism is sometimes used for dimethylfuran, or dimethyl fumarate, this colourless liquid is miscible with water and the majority of organic liquids. This sequencinggrade dimethylformamide is specially purified by a proprietary method and tested to ensure lottol.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Dimethylformamide dmf is a colorless, watersoluble liquid with a faint ammonialike odor. Safety data sheet creation date 12jan2015 revision date 19jan2018 revision number 4 1. It has a role as a polar aprotic solvent and a hepatotoxic agent. N,ndimethylformamide candidate list of substances of very. We provide affordable low cost price quotes on quality and accurate msds and ghs services and documents.
Mdhs70 general methods for sampling airborne gases and vapours. Dimethylformamide is odorless, but technicalgrade or degraded samples often. Identification of the substancemixture and of the companyundertaking. N,n dimethylformamide 68122 hazard summary dimethylformamide is used as an industrial solvent and in the production of fibers, films, and surface coatings. Safety data sheet sds osha hazcom standard 29 cfr 1910. N,ndimethylformamide candidate list of substances of.
Please note that certain data fields will be generic and may or may not reflect the information relevant to the recipient andor the materialpackage size including but not limited to the manufacturersupplier address. Sampler capacity a breakthrough study was performed with a dmf test atmosphere at approximately 46 mgm 3. N, n dimethylformamide dmf is a solvent with a low evaporation rate, useful for preparing solutions with a variety of hydrophobic organic compounds used in molecular biology applications. Dimethylformamide dmf safety data sheet according to federal register vol.
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